Improvement of Antiamoebic Activity of Rokitamycin Loaded in Chitosan Microspheres

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Improvement of Antiamoebic Activity of Rokitamycin Loaded in Chitosan Microspheres

Rokitamycin is a new macrolide containing 16 carbon atoms, strongly inhibitory for Acanthamoeba castellanii, an opportunistic protozoa of humans which cause primarily amoebic keratitis and chronic, but fatal, amoebic granulomatous meningoencephalitis. Chitosan microspheres were prepared as carriers to obtain a controlled release of rokitamycin, able to improve the antiamoebic activity of this d...

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ژورنال

عنوان ژورنال: The Open Drug Delivery Journal

سال: 2008

ISSN: 1874-1266

DOI: 10.2174/1874126600802010038